我们已经回顾了日本，韩国甲状腺微小癌主动监测相关文章。今天看看欧洲相关领域研究现状。读完此文我们已经感到这一策略距离我们理性处理甲状腺癌越来越近！感谢UST团队权威甲状腺专医院核医学科朱旭生教授的认真审校。专业化道路上我们一直在努力。
Europeanperspectiveonactivesurveillanceforpapillarythyroidmicrocarcinoma—areweready?
欧洲甲状腺乳头状微小癌主动监测展望-我们准备好了吗？
翻译：医院普外科刘为民
审校：医院核医学科朱旭生
AgnieszkaCzarniecka1MalgorzataOczko-Wojciechowska2,MarcinBarczynski3
1TheOncologicandReconstructiveSurgeryClinic,
2GeneticandMolecularDiagnosticsofCancerDepartment,M.Sklodowska-CurieNationalResearchInstituteofOncologyGliwiceBranch,Gliwice,Poland;
3DepartmentofEndocrineSurgery,ThirdChairofGeneralSurgery,JagiellonianUniversityMedicalCollege,Kraków,Poland
Contributions:(I)Conceptionanddesign:ACzarniecka;(II)Administrativesupport:None;(III)Provisionofstudymaterialsorpatients:None;(IV)Collectionandassemblyofdata:None;(V)Dataanalysisandinterpretation:None;(VI)Manuscriptwriting:Allauthors;(VII)Finalapprovalofmanuscript:Allauthors.
Correspondenceto:AgnieszkaCzarniecka.TheOncologicandReconstructiveSurgeryClinic,M.Sklodowska-CurieNationalResearchInstituteofOncologyGliwiceBranch,ul.WybrzezeAK15,44-Gliwice,Poland.Email:agnieszka.czarniecka
io.gliwice.pl.Abstract:Duetothegrowingpopulationofpatientswithlow-riskpapillarythyroidcancer,activesurveillanceisincreasinglyconsideredworldwideinsteadofimmediatesurgicalintervention.ThestudyisashortsummaryofthecurrentknowledgeonthissubjectfromtheEuropeanperspective.SofarinEurope,theresultsofoneItaliannon-randomizedprospectiveobservationalstudywitharelativelyshortfollow-up(19months)havebeenpublished.Thestudyassessedagroupof93patientswithlowadvancedpapillarythyroidcancerorwiththesuspicionofcancer(BethesdaV).Thecurrentstudyresultsarenotdifferentfromthoseobtainedinotherpartsoftheworldandconfirmthepossibilityofsafeactivesurveillanceinaproperlyselectedgroupofpatients.TheresultsalsoshouldpromptotherexperiencedEuropeancenterstoinitiatesuchmanagement.Forexample,theDanishresearchershaverecentlyconductedaretrospectiveanalysisofagroupofpatientswhoseaimwastoassesstheprevalenceandcourseofpapillarythyroidmicrocarcinomadependingonthemethodofcancerdetectionandthepossibilityofidentificationofpatientswhoareeligibleforactivesurveillance.
摘要
由于低危甲状腺乳头状癌病人的增加，对低危甲状腺乳头状癌病人实施主动监测而不是确诊后马上进行手术正在全世界范围内进入人们的视野。本研究是关于欧洲在此领域当前状况的短篇总结。在欧洲到目前为止，有一篇来自意大利的非随机前瞻性观察研究的结果经短期随访（19个月）已经发表。这项研究评估了一组93例低危甲状腺乳头状癌病人或可疑癌症病人(BethesdaV级)。当前的研究结果与世界上其他地区的研究没有差异，证实了在选择合适的人群中实施安全主动监测的可能性。这一结果推动了其他有经验的欧洲中心启动了这种处理方式。比如，丹麦研究者最近进行了一项包括例病人的回顾性分析，其目的在于评估甲状腺乳头状微小癌的发病情况和病程，根据癌症检查方法去识别适合主动监测人群的可能性。
WhenthepossibilityofintroducingactivesurveillancetothetherapeuticmanagementofthyroidmicrocarcinomainEuropeisconsidered,severalimportantaspectsmustbetakenintoaccount.TheseaspectsincludeahigherprevalenceofmultinodulargoiterandthyroiditisintheEuropeanpopulation
